The Sandy Fire has forced tens of thousands of residents to evacuate, with mandatory orders affecting areas near Agoura Hills, Calabasas, Hidden Hills, Chatsworth, West Hills, and Lake Manor. Road closures in the region include Bell Canyon Road, Katherine Road, and Santa Susana Pass Road, among others. The fire has destroyed one home and continues to threaten nearby structures. Relative humidity is expected to improve to 60-70% later on Wednesday, which may assist firefighting efforts. However, the ongoing offshore winds could exacerbate fire spread and create additional risks for residents and first responders.